RANDOMIZED CONTROL TRIAL TO ASSESS THE EFFICACY OF CONJUNCTIVAL AUTO-GRAFT & MITOMYCIN – C ON PTERYGIUM SURGERY REOCCURRENCE RATE
| Main Author: | Dr. Ghulam Jafar, Urva Musaddiq, Dr Muhammad Umair |
|---|---|
| Format: | Article |
| Bahasa: | eng |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/1473058 |
Daftar Isi:
- Objective: We aimed to compare the Pterygium recurrence rate followed by the intraoperative use of Conjunctival Auto-graft and Mitomycin – C. Methodology: Our RCT (Randomized Controlled Trial) held at Ophthalmology Department of Allied Hospital, Faisalabad from September 2016 to April 2017 on a total of 130 patients. We divided the 130 patients into two groups through random distribution. Group – I had 65 patients treated with intraoperative Mitomycin – C; whereas, Group – II also had 65 patients treated with Conjunctival Auto-graft. Each group had an equal number of patients but managed differently with a six-month duration follow-up in order to observe the recurrence signs and symptoms in the patients. Results: Reported reoccurrences in Group – I were ten (15.3%); whereas, in Group – II only two occurrences (3%) in the overall follow-up time period. Significant variation was in both groups as reflected in P-value (< 0.05); which implies better research outcomes in Group – II (Conjunctival Auto-graft) in terms of a success rate than Group – I (Mitomycin – C). Conclusion: In visually significant pterygium cases, there is a decreased reoccurrence in the pterygium surgery with the application of Conjunctival Auto-graft than Group – I (Mitomycin – C) adjuvant. Keywords: Mitomycin – C, Conjunctival Auto-graft, Pterygium Surgery, Reoccurrence Rate and Pterygium Excision.