PREVALANCE OF HELICOBACTER INDUCED PEPTIC ULCER IN CIRRHOTIC PATIENTS
| Main Author: | Dr. Ghania Zahid Hussain, Dr. Abeera Tahreem, Dr. Sobia Nawaz |
|---|---|
| Format: | Article |
| Bahasa: | eng |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/1443480 |
Daftar Isi:
- Objective: Infection caused by the Helicobacter pylori increases the danger of ulcer of mucus membrane in the patients suffering of liver disease. The part played by Helicobacter pylori in the initiating of ulcer in the patients of chronic liver disease is still contentious. The main aim is study is to know that if Helicobacter pylori play any role the patients suffering of chronic liver disease. Methodology: In this research work, 60 patients of chronic liver disease were selected. Endoscopy was used to discover the peptic ulcer in those patients of chronic liver disease. Serum of these participants was checked for H. pylori antibodies with the help of a special commercial kit ELISA. T student & fisher test was utilized for statistical investigation. Results: Peptic ulcer was discovered in active condition in only 9 patients of chronic liver disease. Among them, eight patients were found positive for H. pylori antibodies. The percentage of these patients was more than eighty-eight percent. From the remaining fifty-one patients, thirty-one patients were found positive for H. pylori antibodies. The percentage of these patients was about sixty-one percent. Conclusion: Infection caused by H. pylori in the patients suffering of chronic liver disease with ulcer of mucus membrane are showing the similar arrangement as explained by the patients of chronic liver disease without ulcer of that particular kind. So, it was assumed that the cause of this disease of peptic ulcer in patients of cirrhotic disease could be linked to infection of H. pylori. But this result was not factually confirmed by this research work. Key Words: Helicobacter pylori, Peptic ulcer, chronic disease, liver, ELISA, antibodies.