POLYCYSTIC IN OVARIAN SYNDROME AND ITS VARIOUS TREATMENT STRATEGIES
| Main Author: | Mudasir Maqbool, Dr. Nazia Nasir, Dr. Sajjad Mustafa |
|---|---|
| Format: | Article |
| Bahasa: | eng |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/1412698 |
Daftar Isi:
- Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder, leading to several health complications, including menstrual dysfunction, infertility, hirsutism, acne, obesity, and metabolic syndrome. Polycystic ovary syndrome (PCOS) is a complex condition characterized by elevated androgen levels, menstrual irregularities, and/or small cysts on one or both ovaries. PCOS affects as many as 10% of reproductive-age women when using the NIH criteria for diagnosis, and up to 18% of reproductive-age women are diagnosed with PCOS as per the Rotterdam criteria. The exact pathophysiology of PCOS is complex and remains largely unclear. Genetic and environmental contributors to hormonal disturbances combine with other factors, including obesity, ovarian dysfunction and hypothalamic pituitary abnormalities to contribute to the etiology of PCOS. PCOS is a highly prevalent heterogeneous syndrome of clinical and/or biochemical androgen excess, ovulatory dysfunction and polycystic ovaries (PCO). Despite it being one of the most common reproductive health problems of women, its effective treatment remains a significant challenge to medical profession. Further research is needed to find the exact etiology, methods of prevention and proper management of this endocrine disorder. Keywords: Polycystic ovary syndrome, Hyperandrogenism, Insulin resistance, obesity.