Unfolding brain tractography
Main Authors: | Heuer, Katja, Toro, Roberto |
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Format: | Proceeding poster Journal |
Bahasa: | eng |
Terbitan: |
, 2015
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Subjects: | |
Online Access: |
https://zenodo.org/record/1343372 |
Daftar Isi:
- An A0 poster which is designed for fabric print and can be cut and sewed into two bags. The poster was presented at the 2015 Annual Meeting of the Organization for Human Brain Mapping (OHBM) in Hawaii, 14–18 June. Project: The geometry of the human neocortex is very complex: 2⁄3 of its surface are hidden within folds. However, its topology is simply that of a surface. This simplicity can be recovered by neocortical unfolding, which has become a main visualisation tool in neuroimaging. Similarly, under the incredible geometric complexity of the human connectivity networks may lay a more simple organisation. Indeed, the first axonal connections develop when the shape of the brain is still not very different from a neural tube, and follow its main longitudinal and transverse directions (Nieuwenhuys, 1998). In the adult primate brain – humans included – it has been suggested that all connections follow 3 main orthogonal directions (Wedeen 2012). Methods to unfold brain connectivity could in consequence provide also a simpler representation of tractography data, allowing the researchers to obtain a more intuitive grasp of their results. Here we present our first results on tractography unfolding. Our approach is similar to that used by geographers to map the surface of the earth, but using all 3 dimension. We have contained brain tractography data within a cylinder or a sphere, and unfolded fibres by unfolding the space within them. Depending on the orientation of the tractography data within the containing objects, we can produce different views on brain connectivity.