Daftar Isi:
  • Specific learning disorder is characterized by persistent and impairing difficulties with learning foundational academic skills in reading, writing, and/or math and is not associated with other psychiatric or neurological diseases. It may be complex and multifactorial, involving a combination of polygeneity and heterogeneity. There are better investigated genetic aspects of specific reading disability. In the human genome there were discovered at least 9 candidate loci and 14 candidate genes with different significance levels. Genetic studies of specific writing disability were not accomplished. In the modern technological and computerized world there is valued mostly mathematical ability and so researchers are interested in the nature of math ability and math talent, but not of math disability. There were found two genes and a certain domain sequences, variants of which are associated with math abilities. Further molecular genetic researches of sufficiently large samples are necessary to understand the genetic nature of specific learning disorders.