Improving Protein-Protein Interaction Prediction by Using Encoding Strategies and Random Indices

Main Author: Essam Al-Daoud
Format: Article
Bahasa: eng
Terbitan: , 2011
Online Access: https://zenodo.org/record/1330861
ctrlnum 1330861
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language eng
format Journal:Article
Journal
author Essam Al-Daoud
title Improving Protein-Protein Interaction Prediction by Using Encoding Strategies and Random Indices
publishDate 2011
url https://zenodo.org/record/1330861
contents A New features are extracted and compared to improve the prediction of protein-protein interactions. The basic idea is to select and use the best set of features from the Tensor matrices that are produced by the frequency vectors of the protein sequences. Three set of features are compared, the first set is based on the indices that are the most common in the interacting proteins, the second set is based on the indices that tend to be common in the interacting and non-interacting proteins, and the third set is constructed by using random indices. Moreover, three encoding strategies are compared; that are based on the amino asides polarity, structure, and chemical properties. The experimental results indicate that the highest accuracy can be obtained by using random indices with chemical properties encoding strategy and support vector machine.
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