Comparison of Intrathecal Midazolam and Fentanyl used as an adjuvant with Hyperbaric Bupivacaine in infraumbilical surgeries: A prospective, randomized, double-blind, interventional study
| Main Authors: | Dr. Mahesh Kumar Meena, Dr. Rajeev Sharma, Dr. Vinod Kumar Meena, Dr. Dilip Raj |
|---|---|
| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/1324139 |
Daftar Isi:
- Abstract— Post-operative pain management remains a challenge. Various combination of medicines are used to reduce post operative pain. So study was designed to compare the effect of Midazolam and Fentanyl adjuvant to Bupivacaine in reducing pain in infra-umblical surgeries It was observed in thia study that duration of analgesia was 197.6±9.8 minutes when bupivacaine was used alone, while it increased to 272.8±10.9, and 286±10.4 minutes when bupivacaine was used in combination with fentanyl and midazolam respectively. The total duration of analgesia in midazolam group was significantly more than Fenetanyl and Saline group. Present study demonstrated that midazolam produce longer duration of post-operative analgesia when compared to fentanyl. Mean VAS scores at various intervals were compared in all the three groups, it was found without significant variation till 2 hours of surgery but after that upto 3 hours it was minimum (<0.05) in Midozolam group and after 3 hours it significantly less (<0.05) in Fenetanyl group. So it can be concluded from this study that adding Midozolam with Bupivacaine is good for analgesia.