COMPARATIVE ANALYSIS OF CHEMICAL COMPOSITION OF BUCHHOLZIA CORIACEA ETHANOL LEAF-EXTRACT, AQUEOUS AND ETHYLACETATE FRACTIONS
| Main Author: | Ibiam, Udu Ama, Alum, Esther Ugo, Aja, Patrick Maduabuchi, Orji, Obasi Uche, Ezeani Nkiru Nwamaka, Ugwu, Okechukwu Paul-Chima |
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| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/1311171 |
Daftar Isi:
- The medicinal value of plants depends on their chemical constituents that provide a definite physiological action on the human body. Knowledge of chemical constituents of plant is necessary for the discovery of therapeutic agents of importance and their precursors. This work is aimed at evaluating and comparing the chemical composition of Buchholzia coriacea ethanol leaf-extract, aqueous and ethylacetate fractions of the ethanol leaf-extract. The phytochemical, mineral and vitamin constituents of the extract and fractions were analyzed using standard methods. Proximate composition of the dry leaves was also determined using standard method. Phytochemical constituents (mg/100g) in all samples were in the order of: Terpenoids>phenols>alkaloids>flavonoids>tannins>saponins>steroids>glycosides. Some phytochemicals were significantly (P<0.05) higher in the extract than fractions. The aqueous fraction contained vitamins B and C in significantly (P<0.05) higher amounts while ethylacetate fraction contained mainly vitamins A, D, E and K. The mineral compositions (mg/100g) in extract and fractions were in the order of Fe>Ca>Mg>K>P>Na>Cu while result of proximate analysis (%) of the dry leaf was in the order of carbohydrates>protein>moisture>fibre>ash>fats. The acute toxicity study showed that the ethanol leaf-extract caused no death to the rats even at 5000 mg/kg body weight. The results show that Buchholzia coriacea contain some phytochemicals, vitamins and minerals in adequate concentration which could be responsible for the physiological activities of this plant. Therefore, this study provides scientific evidence for the use of this plant by rural dwellers in the management of various diseases. Key words: Phytochemicals, Buchholzia coriacea, Minerals and Vitamins.