METABOLOMICS: CURRENT TECHNOLOGIES AND FUTURE TRENDS
| Main Author: | Dr. A. Krishnamanjari pawar*, T .Samhitha, B. Prasanna, MD. Asif, M. Lavanya. |
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| Format: | Article Journal |
| Bahasa: | eng |
| Terbitan: |
, 2018
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/1287901 |
Daftar Isi:
- The emerging field of metabolomics had profound importance in recent years as its wide applications in the field of drug discovery and drug development. With recent advances in the field of metabolomics it can be proved as a major tool in the process of drug discovery and development. In the agricultural/chemical industry, metabolomics may be used to develop herbicides and pesticides With increasing importance being placed on health and safety related aspects of our food, metabolomics can potentially be a valuable tool to monitor and improve the quality of what we eat; for example, in food processing and quality control, or in plant breeding for improved crop varieties and in the development of novel food stuffs. The present review reveals the importance of metabolomics in drug discovery along with recent advances in the techniques of metabolomics along with its wide applications in various fields like drug discovery, drug toxicity profiling, food industries especially in food and allied beverages testing. A range of analytical technologies has been employed to analyze metabolites in different organisms, tissues, or fluids. Mass spectrometry coupled to different chromatographic separation techniques, such as liquid or gas chromatography or NMR, are the major tools to analyze a large number of metabolites simultaneously. All of these so-called ’omics approaches, including genomics, transcriptomics, proteomics and metabolomics are considered important tools to be applied and utilized to understand the biology of an organism and its response to environmental stimuli or genetic perturbation. Keywords: Metabolome, metabolite, metabolomics, systems biology, phenotyping.