Figure 5.(a)Linear (y=0.45x + 57.74) dose-response relationship between plasma propranolol to % β- adrenergeric blockade derived from healthy study participants and translate into patients with angina pectoris. This image has been adapted from(Pine et al., 1975).-The Brain and Propranolol Pharmacokinetics in the Elderly
| Main Authors: | Andy R. Eugene, Wayne T. Nicholson |
|---|---|
| Format: | info Image |
| Bahasa: | eng |
| Terbitan: |
, 2015
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| Subjects: | |
| Online Access: |
https://www.edusoft.ro/brain/index.php/brain/issue/view/30 |
Daftar Isi:
- Apharmacodynamic model,with parameters in the table below, may be used to visualize the propranolol concentration-effect (β-blockade) relationship in patients suffering from angina pectoris. These results have been adapted from the Pine et al article published in Circulation in 1975 which identified a linear relationship plasma Propranolol (ng/mL) to an effect of % β-Adrenergic Blockade in a single-oral dose of 40mg Propranolol in exercising individuals (Pine et al., 1975).