The effect of NADP on some values of the renal acid-regulating function at experimental diabetes mellitus
| Main Author: | Grytsiuk, M. I. |
|---|---|
| Format: | Article |
| Terbitan: |
, 2017
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| Online Access: |
https://zenodo.org/record/1145444 |
Daftar Isi:
- Grytsiuk M. I. The effect of NADP on some values of the renal acid-regulating function at experimental diabetes mellitus. Journal of Education, Health and Sport. 2017;7(11):319-324. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1145444 http://ojs.ukw.edu.pl/index.php/johs/article/view/5203 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2017; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 06.11.2017. Revised: 20.11.2017. Accepted: 30.11.2017. UDC 616.632/.633:615.015.4:577.15.013:616.379-008.64 THE EFFECT OF NADP ON SOME VALUES OF THE RENAL ACID-REGULATING FUNCTION AT EXPERIMENTAL DIABETES MELLITUS M. I. Grytsiuk Higher State Educational Institution of Ukraine «Bukovinian State Medical University”, Chernivtsi, Ukraine m.grytsiuk@gmail.com Abstract Diabetes is a significant social problem, since it leads both to disability and high mortality rate. The experiment involved 32 sexually mature nonlinear males of white rats. Experimental groups of animals were administered a single streptozotocin dose of 70 mg/kg intraperitoneally and NADP – 30 mg/kg. The animals in the experimental groups were slaughtered and studied on the 11th, 21st and 31st days after streptozotocin administration. The studies have shown that NADP affects the metabolism, reduces the production of acids and, as a result, reduces the excretion of acids by the kidneys in experimental animals. Key words: diabetes mellitus, nephropathy, acid-regulating function, streptozotocin, diuresis.