Histoenzymic determination of activity of alkaline phosphatase and succinate dehydrogenase in the renal tissue of rats at NADP administration on the background of 31-days experimental diabetes mellitus
| Main Author: | Grytsiuk, M. I. |
|---|---|
| Format: | Article |
| Terbitan: |
, 2017
|
| Online Access: |
https://zenodo.org/record/1119068 |
Daftar Isi:
- Grytsiuk M. I. Histoenzymic determination of activity of alkaline phosphatase and succinate dehydrogenase in the renal tissue of rats at NADP administration on the background of 31-days experimental diabetes mellitus. Journal of Education, Health and Sport. 2017;7(10):222-229. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1119068 http://ojs.ukw.edu.pl/index.php/johs/article/view/5150 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2017; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 10.10.2017. Revised: 27.10.2017. Accepted: 30.10.2017. UDC 616. 616.61-092-085.355:577.152.1:616.379-008.64 HISTOENZYMIC DETERMINATION OF ACTIVITY OF ALKALINE PHOSPHATASE AND SUCCINATE DEHYDROGENASE IN THE RENAL TISSUE OF RATS AT NADP ADMINISTRATION ON THE BACKGROUND OF 31-DAYS EXPERIMENTAL DIABETES MELLITUS M. I. Grytsiuk Higher State Educational Institution of Ukraine «Bukovinian State Medical University”, Chernivtsi, Ukraine m.grytsiuk@gmail.com Abstract The article presents data on the activity of some enzymes of rats’ renal tissue in experimental diabetes mellitus in the early period of its formation. It was found that at 31 days of the experiment, the administration of NADP significantly increases the activity of ALP by more than twice, thereby improving the functioning of the proximal tubules in particular, and restores almost normal SDH activity, which allows us to assume that the positive metabolic effects of NADP are not only at the level of general metabolism, but also specifically at the organ level - the kidneys. Key words: diabetes mellitus, streptozotocin, alkaline phosphatase, succinate dehydrogenase.