Human CpG- Loci Correlation with Mathematical Generating Functions & SNP/ INDELs
| Main Author: | Praharshit Sharma |
|---|---|
| Format: | info publication-proposal Journal |
| Terbitan: |
, 2017
|
| Subjects: | |
| Online Access: |
https://zenodo.org/record/1118066 |
Daftar Isi:
- There are more than 28 million CpG loci (aka CpG dinucleotides, CpG sites) in the human genome. Due to the increasing interest in epigen-etic research—DNA methylation in particular—there is a strong need for a reference database where researchers can find information about individual CpG loci. Unlike other genomic loci, such as genes or SNPs, CpG loci lack a formal nomenclature. As a result, each CpG locus does not have a unique and unambiguous identifier to be used for clear reference to the locus in databases and other communications. Here, in my Research Proposal, we aim to address the "Algorithmic" problem of identifying the CpG loci themselves "within" the CpG islands - while looking for coding regions of genes.
- This is a Research Proposal Draft, designed for Project Funding, by the author.