A Study on Cancer-Cell Invasion Based On the Diffuse Interface Model
| Main Authors: | Zhang Linan, Jihwan Song, Dongchoul Kim |
|---|---|
| Format: | Article |
| Bahasa: | eng |
| Terbitan: |
, 2010
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| Subjects: | |
| Online Access: |
https://zenodo.org/record/1082061 |
Daftar Isi:
- In this study, a three-dimensional haptotaxis model to simulate the migration of a population of cancer cells has been proposed. The invasion of cancer cells is related with the hapto-attractant and the effect of the interface energies between the cells and the ECM. The diffuse interface model, which incorporates the haptotaxis mechanism and interface energies, is employed. The semi-implicit Fourier spectral scheme is adopted for efficient evaluation of the simulation. The simulation results thoroughly reveal the dynamics of cancer-cell migration.