ANTI-INFLAMMATORY EFFECT OF BETA-BETA (LUNASIA AMARA ) IN WISTAR RATS
| Main Author: | Hasnaeni, Hasnaeni |
|---|---|
| Format: | Proceeding PeerReviewed Book |
| Bahasa: | eng |
| Subjects: | |
| Online Access: |
http://repository.umi.ac.id/218/1/336552412_ANTIINFLAMMATORY_EFFECT_OF_BETA-BETA_Lunasia_amara_in_WISTAR_RATS_KESIMPULAN_Bayam_duri_Ammaranthus_sp http://repository.umi.ac.id/218/ https://knepublishing.com/index.php/Kne-Life/issue/view/135 |
Daftar Isi:
- Introduction. The Beta-beta (Lunasia amara) extract is being used orally and topically in traditionalIndonesia for the treatment of leg swelling, skin diseases and inflammation or irritation of the eyes. Theanti-inflammatory effect of beta-beta wood were tested in rats induced Complete Freund’s Adjuvant(CFA) 0,1%.Aim. Test the effect anti-inflammatory of beta-beta wood (Lunasia amara) in Wistar rats.Methods. Anti-inflammatory effects of beta-beta was observed at the foot of Wistar rats inducedComplete Freund's Adjuvant (CFA). Animals were divided into 6 groups with each group consisting of 6animals: the group given extract beta-beta at a dose of 5 mg/kg body weight (BW) and 10 mg/kg BW,group given a fraction of beta-beta and a control group that controls positive, normal controls andnegative controls. Antiinflammatory effect was observed through a decrease in volume of edema in ratsinduced foot CFA. Edema volume measurements using a pletismometer.Results. Beta-beta wood has anti-inflamamtory effect in Wistar rats induced CFA. The measurementresults between the group given the extract and the fraction of the beta-beta wood compared withdiclofenac sodium control group showed no significant difference (p˂0,05).Conclusion. Beta-beta wood (Lunasia amara) has anti-inflammatory effects in Wistar rats.Keyword : Anti-inflammatory, beta-beta (Lunasia amara), Wistar rats, Complete Freund’s adjuvant(CFA), pletismometer