STABILITY EVALUATION OF CREAM EXTRACT OF NEEM, GOTU KOLA AND SOURSOP FOR DERMATITIS TREATMENT IN DOG
| Main Authors: | Suartha, I Nyoman, Sudimartini, Luh Made, Wijayanti, Ni Putu Ayu Dewi |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | ind |
| Terbitan: |
The Faculty of Veterinary Medicine, Udayana University
, 2021
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| Online Access: |
https://ojs.unud.ac.id/index.php/buletinvet/article/view/47068 https://ojs.unud.ac.id/index.php/buletinvet/article/view/47068/41109 |
Daftar Isi:
- This study aims to evaluate the stability of herbal extract creams with a combination of neem leaves, gotu kola, and soursop extract to cure dermatitis complex in dogs., This herb extract has been able to inhibit in vitro the growth of bacteria that cause dermatitis. This research was conducted in the Laboratory of Non-Sterile Formulation and Technology at the Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Udayana University. Cream preparations were made in three formulations; each formulation was evaluated for stability at room temperature. Evaluation of the stability of cream includes organoleptic test, homogeneity test, pH test, adhesion test, spreadability test, and viscosity test. The results showed the cream was stable at room temperature for one month and the stable formula was formula 1. It can be concluded that the herb of formula 1 extract cream was stable at room temperature for one month.
- Penelitian ini bertujuan untuk mengevaluasi stabilitas dari krim ekstrak herbal dengan komposisi kombinasi ekstrak daun nimba, pegagan, dan sirsak untuk membantu persembuhan penyakit radang kulit (Dermatitis) kompleks pada anjing. Secara in vitro ekstrak herbal di atas telah mampu menghambat pertumbuhan bakteri penyebab dermatitis. Penelitian ini dilakukan di Laboratorium Formulasi dan Teknologi Non Steril Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Udayana.Sediaan krim dibuat dalam tiga formulasi, masing-masing formulasi dari sediaan tersebut di evaluasistabilitasnya pada suhu kamar. Evaluasi stabilitas sediaan krim meliputi uji organoleptik, uji homogenitas, uji pH, uji daya lekat, uji daya sebar, dan uji viskositas. Hasil yang telah didapat sediaan krim stabil pada suhu ruang selama satu bulan dan formula yang stabil adalah formula 1. Disimpulkan krim ekstrak herbal formula 1 stabil pada suhu ruang selama satu bulan.