ANTIBODY TITER OF LOCAL DOGS SIX MONTHS ON RABIES VACCINATION
| Main Authors: | Sudarmayasa, I Nengah, Suardana, Ida Bagus Kade, Suartha, I Nyoman |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
The Faculty of Veterinary Medicine, Udayana University
, 2020
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| Online Access: |
https://ojs.unud.ac.id/index.php/buletinvet/article/view/44158 https://ojs.unud.ac.id/index.php/buletinvet/article/view/44158/33817 |
Daftar Isi:
- Rabies is a zoonotic disease that can be transmitted from animals to humans. Most cases of rabies (98%) were caused by the bite of dogs infected with rabies, while the rest by the cats. This study aims to determine the antibody titer six months y.o local dog after the rabies vaccination using vaccines rabisin. This research was conducted in three stages, namely: taking blood samples in the villages of Buduk and Sading, serum sampling and serum testing using an enzyme linked immunosorbent assay (ELISA) test using 19 samples of local dogs with random blood sampling. The results showed that from 19 samples tested 17 samples (89%) had protective antibody titers (seropositive) and two samples (11%) did not have protective (seronegative) antibody titers. Seropositive was the value of Optical Density (OD) above 0, 5 IU, while seronegative is the value of Optical Density (OD) below 0.5 IU.
- Rabies merupakan penyakit zoonosis yaitu, penyakit yang dapat ditularkan dari hewan ke manusia. Sebagian besar kasus rabies (98%) disebabkan oleh gigitan anjing penderita rabies, sedangkan sisanya oleh kucing. Penelitian ini bertujuan untuk mengetahui titer antibodi anjing lokal enam bulan pasca vaksinasi rabies menggunakan vaksin rabisin. Penelitian ini dilakukan tiga tahap, yaitu: pengambilan sampel darah di Desa Buduk dan Sading, pemisahan serum dan pengujian serum dengan uji enzym linked immunosorbent assay (ELISA) menggunakan 19 sampel anjing lokal dengan pengambilan darah secara acak. Hasil penelitian menunjukkan dari 19 sampel yang diuji sebanyak 17 sampel (89%) memiliki titer antibodi protektif (seropositif) dan dua sampel (11%) belum memiliki titer antibodi protektif (seronegatif). Seropositif adalah nilai Optical Density (OD) di atas 0,5 IU, sedangkan seronegatif adalah nilai Optical Density (OD) di bawah 0,5 IU.