EFFECTIVENESS OF SOURSOP LEAF EXTRACT To Microsporum gypseum CAUSE DERMATITIS COMPLEX ON DOG
| Main Authors: | serlin, angelina, Suartha, I Nyoman, Rompis, Aida Louise Tenden |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | ind |
| Terbitan: |
The Faculty of Veterinary Medicine, Udayana University
, 2020
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| Online Access: |
https://ojs.unud.ac.id/index.php/buletinvet/article/view/43855 https://ojs.unud.ac.id/index.php/buletinvet/article/view/43855/36167 |
Daftar Isi:
- Soursop leaf (Annona muricata L) contains active compounds such as flavonoids, saponins, and tannins that act as antifungals. This study aims to determine the ability of soursop leaf extract in inhibiting the growth of Microsporum gypseum, which causing dermatitis complex in dogs. The ability of soursop leaf extract to inhibit the growth of M. gypseum was tested using the agar plate diffusion method (Kirby Bauer) with slight modification. Complete randomized design (RAL) with four treatment, i.e., soursop leaf extract 0%, 5%, 10%, and 25%, with four replication and ketoconazole as a positive control was used in the study. The results showed that the inhibitory zones formed at concentrations of 5%, 10%, and 25% were 2.50 mm ± 0.00, 3.55 mm ± 0.00, and 5.00 mm ± 0, 58, respectively. Statistically, there was a highly significant difference (p <0.01) between the average inhibitory zone of each treatment. Conclusion based on the test effectiveness of the soursop leaf extract is able to inhibit the growth of M. gypseum, which causing dermatitis complex in dogs.
- Daun sirsak (Annona muricata L.) mengandung senyawa aktif seperti flavonoid, saponin dan tanin yang berperan sebagai antijamur. Penelitian ini bertujuan untuk mengetahui kemampuan ekstrak daun sirsak dalam menghambat pertumbuhan jamur Microsporum gypseum penyebab dermatitis kompleks pada anjing. Kemampuan ekstrak daun sirsak dalam menghambat pertumbuhan jamur M. gypseum diuji dengan modifikasi metode difusi lempeng agar (Kirby Bauer) dengan teknik sumuran. Rancangan penelitian yang digunakan adalah rancangan acak lengkap (RAL) dengan 4 perlakuan yaitu ekstrak daun sirsak konsentrasi 0%, 5%, 10%, dan 25%, dengan ulangan 4 kali dan larutan ketokonazol sebagai kontrol positif. Hasil penelitian menunjukan bahwa rataan besar zona hambat yang terbentuk pada konsentrasi 5%, 10%, dan 25% secara berturut- turut yaitu 2,50 mm ± 0,00, 3,55 mm ± 0,00, dan 5,00 mm ± 0,58. Secara statistik ada perbedaan yang sangat nyata (p<0,01) antara rataan besar zona hambat masing-masing perlakuan. Disimpulkan ekstrak daun sirsak mampu menghambat pertumbuhan jamur M. gypseum penyebab dermatitis kompleks pada anjing.