Cytotoxicity Assay From Fractions of Hedyotis corymbosa Extract Against Breast Cancer Cell Line T47D
| Main Authors: | Andriyani, Rina, Risdian, Chandra, Udin, Zalinar |
|---|---|
| Format: | Article info application/pdf Document |
| Bahasa: | eng |
| Terbitan: |
Indonesian Society for Cancer Chemoprevention
, 2011
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| Online Access: |
https://ijcc.chemoprev.org/index.php/ijcc/article/view/29 https://ijcc.chemoprev.org/index.php/ijcc/article/view/29/30 |
Daftar Isi:
- Drug discovery for cancer medication is the most important effort that researcher do at this time. Indonesia bio diversities have possibility as a cancer medicine sources. Finding a herbal medicine for cancer treatment is a first step to find a right cancer medicine in the future. This research has already completed for the earlier another research. Some fractions of Hedyotis corymbosa extract has been analyzed using Sulforhodamine B method with UV wavelength 515 nm against T47D cell line, a human breast cancer. There are Hexane extract, Methylene chloride extract and Ethyl acetate extract, and give inhibitory concentration 50 (IC50) of 33.45 μg/ml, 54.59 μg/ml and 52.58 μg/ml, respectively. Ethanolic extract, itself has IC50 of 61.57 μg/ml, whereas IC50 value of Cisplatinum is 9.63 μg/ml. There is a difference between the ethanolic extracts with the other fraction.Keywords: breast cancer, herbal medicine, T47D, Hedyotis corymbosa