Physical Stability Test of Leaf Powder Ethanol Extract of Ciplukan Leaf (Physalis angulata L.) as Anti-Fungal
| Main Authors: | H. Ambo Lau, Sulfiyana, Herman, Herman |
|---|---|
| Format: | Article info application/pdf Journal |
| Bahasa: | ind |
| Terbitan: |
Nursing of Politeknik Sandi Karsa
, 2020
|
| Online Access: |
https://akper-sandikarsa.e-journal.id/JIKSH/article/view/472 https://akper-sandikarsa.e-journal.id/JIKSH/article/view/472/348 |
Daftar Isi:
- Ciplukan (Physalis angulata L.) is a seasonal herbaceous plant from the Solanaceae family which has many benefits, one of which is as an antifungal. Research has been carried out on the formulation and physical stability test of the ethanol extract of the leaves of Ciplukan (Physalis angulata L.) as anti-fungi. The goal is to find out that ciplukan leaves contain chemical substances that can inhibit the growth of fungi on the skin and can be formulated into powder preparations. This research is a laboratory experimental research. This research includes identification tests for alkaloids, flavonoids, saponins, steroids, and tannins. The powder formulations were FI (without extract), FII (extract 10%), and FIII (extract 20%). The stability test of the preparation includes the organoleptic test, homogeneity, fine degree, pH, adhesion, and hedonic test. The results of the research identified positive compounds containing alkaloids, flavonoids, saponins, and tannins. In the stability test, all formulations showed the results according to the literature, the hedonic test was not irritating and formula FII was preferred. The conclusion is that the ethanol extract of ciplukan leaves contains antifungal compounds and can be formulated into powder with good stability
- Ciplukan (Physalis angulata L.) adalah tanaman semusim berupa herba dari famili Solanacea yang memiliki banyak manfaat salah satunya sebagai antijamur. Telah dilakukan penelitian mengenai Formulasi dan Uji Stabilitas Fisik Sediaan Bedak Tabur Ekstrak Etanol Daun Ciplukan (Physalis angulata L.) sebagai Anti Fungi. Tujuan mengetahui daun ciplukan memiliki kandungan kimia yang dapat menghambat pertumbuhan jamur pada kulit dan dapat diformulasikan menjadi sediaan bedak tabur. Penelitian ini adalah penelitian eksperimen laboratorium. Penelitian ini meliputi uji identifikasi senyawa alkaloid, flavonoid, saponin, steroid, dan tanin. Formulasi bedak tabur yaitu FI (tanpa ekstrak), FII (ekstrak 10%) dan FIII (ekstrak 20%). Uji stabilitas sediaan meliputi uji organoleptis, homogenitas, derajat halus, pH, daya lekat, dan uji hedonik. Hasil dari penelitian identifikasi senyawa positif mengandung alkaloid, flavonoid, saponin dan tanin. Pada uji stabilitas semua formulasi menunjukkan hasil sesuai literatur, uji hedoniknya tidak mengiritasi dan formula FII yang lebih disukai. Kesimpulannya bahwa ekstrak etanol daun ciplukan mengandung senyawa antijamur dan dapat diformulasikan menjadi bedak tabur dengan kestabilan yang baik