Enzim Transferase dengan Bilirubin Total Penderita Ikterus Obstruktif
| Main Author: | Fajrian, Fatima Maulidina |
|---|---|
| Format: | Article info application/pdf Journal |
| Bahasa: | ind |
| Terbitan: |
Nursing of Politeknik Sandi Karsa
, 2020
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| Online Access: |
https://akper-sandikarsa.e-journal.id/JIKSH/article/view/240 https://akper-sandikarsa.e-journal.id/JIKSH/article/view/240/204 |
Daftar Isi:
- Post-hepatic obstructive jaundice is jaundice that caused by an obstruction in the bile ducts that leads to disruption of bile flow between the liver and duodenum. The function of the liver can be measured by examining the activity of serum aminotransferase, known as Serum Glutamic Oxaloacetic Transaminase and Serum Glutamic Pyruvic Transaminase. SGOT, SGPT, and bilirubin is one of the liver productions in which if liver damage occurs, there will be abnormalities in the results. The purpose of this study was to determine the relationship between transferase enzymes and total bilirubin in obstructive jaundice patients. This study was an Observational analytic approach with a cross-sectional design, and the sampling technique was purposive sampling and obtained a sample of 40 people. Patients data were obtained from secondary data with medical records. The bivariate test is done by Spearman’s correlation test. The result showed that there is a good correlation between SGOT levels and total bilirubin levels (p-value = 0.001), with a correlation value of 0.498, also SGPT levels and total bilirubin levels (p-value = 0.011), with a correlation value of 0.397. The conclusion is an increase of total bilirubin levels in obstructive jaundice patients will be accompanied by an increase of SGOT and SGPT levels
- Ikterus obstruktif post-hepatik merupakan ikterus yang terjadi akibat adanya suatu sumbatan pada saluran empedu yang mengakibatkan terjadinya gangguan aliran empedu antara organ hati dengan duodenum. Fungsi hati dapat diukur dengan cara memeriksa aktivitas enzim serum, salah satunya serum aminotransferase yaitu Serum Glutamic Oxaloacetic Transaminase (SGOT) dan Serum Glutamic Piruvic Transaminase (SGPT). SGOT, SGPT dan bilirubin merupakan salah satu produksi dari hati yang dimana jika terjadi kerusakan hati maka akan terjadi kelainan pada hasil enzim hati dan bilirubin total. Tujuan penelitian ini adalah mengetahui hubungan antara enzim transferase dengan bilirubin total pada penderita ikterus obstruktif di RSUD Dr. H. Abdul Moeloek Provinsi Lampung tahun 2019. Penelitian ini merupakan penelitian analatik observasional dengan pendekatan cross sectional. Pengambilan sampel pada penelitian ini menggunakan metode purposive sampling dan didapatkan sampel sebanyak 40 orang. Data pasien diperoleh dari data sekunder dengan hasil rekam medik. Uji bivariat menggunakan uji korelasi Spearman’s. Hasil penelitian menunjukkan ada korelasi yang baik antara kadar SGOT dengan kadar bilirubin total (p-value =0.001), dengan nilai korelasi yaitu 0.498.Ada korelasi yang baik antara kadar SGPT dengan kadar bilirubin total (p-value =0.011), dengan nilai korelasi yaitu 0.397. Kesimpulannya, peningkatan kadar bilirubin total pada pasien ikterus obstruktif akan diiringi dengan peningkatan kadar SGOT dan SGPT