Similarity Check: Efek Serbuk Bunga Rosella Merah (Hibiscus sabdariffa L.) terhadap Ekspresi IL-10 pada Sukarelawan Sehat
| Main Authors: | Syahrana, Nur Azizah, Akrom, Akrom, Darmawan, Endang |
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| Format: | Lainnya NonPeerReviewed Book |
| Bahasa: | eng |
| Terbitan: |
Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia
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| Subjects: | |
| Online Access: |
http://eprints.uad.ac.id/18668/1/Efek_Serbuk_Bunga_Rosella_Merah__Hibiscus_sabdarif.pdf http://eprints.uad.ac.id/18668/ |
Daftar Isi:
- Background: Rosella calyx (Hibiscus sabdariffa L.) contain phenol and anthocyanin flavonoids that have activity as antioxidants and can stimulate the immune system. Objective: The purpose of this study was to investigate the effect of rosella powder capsule on expression IL-10 using pre and post test method on 21 healthy volunteers who fulfilled inclusion criteria and willing to fill informed consent. Methods: Volunteers were given rosella powder in capsules form with 500 mg dose for 30 days and IL-10 was examined using flowsitometric method on days 0.30 and 45. The results were analyzed using SPSS with wilcoxon test. Results: The value of IL10 expression in the 0.30 and 45 day volunteers were 0.42 ± 0.24; 0.83 ± 0.47 and 1.06 ± 0.67. These results showed that IL-10 expression had an effect on day 0 to 30 (p < 0.05) and IL-10 expression did not affect the 30 day of the 45 (p > 0.05). Conclusion: administration of rosella powder capsules (Hibiscus sabdariffa L.) dose 500 mg/day for 30 days increased the expression of IL-10, but within normal limits on healthy volunteers. Keywords: roselle, IL-10 expression, healthy volunteers