Formulation and evaluation of extended release spheroids for antidepressant drug by MUPS
| Main Authors: | Kumar, Amrendra, Singh, Vikram, Juyal, Divya, Rawat, Geeta |
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| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Creative Pharma Assent
, 2014
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| Subjects: | |
| Online Access: |
https://japtronline.com/index.php/joapr/article/view/34 https://japtronline.com/index.php/joapr/article/view/34/34 |
Daftar Isi:
- The extended release spheroids was Formulated using Ethyl Cellulose, Povidone and Triacetin as a Coating material and evaluated the effect of change in weight build up on drug release profile. Optimization of extended release coating by 19% build up of EC/PVP-K30 of formulation (F4), in which the formulation is formulated by Reservoir system and the drug release depends on coating thickness of EC/PVP-K30. As concentration of coating weight buildup increases. which increases the thickness of coating on the reservoir system hence release retarded and transformed into an extended release system.