Formulation and evaluation of colon targeted dosage form of prednisolone tablet using sterculia gum
| Main Authors: | Raghuvanshi, Neha Singh , Goswami, Laxmi, Kothiyal, Preeti |
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| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Creative Pharma Assent
, 2014
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| Subjects: | |
| Online Access: |
https://japtronline.com/index.php/joapr/article/view/32 https://japtronline.com/index.php/joapr/article/view/32/32 |
Daftar Isi:
- Matrix tablets of Prednisolone were prepared by wet granulation method using various proportions of Sterculia gum with Carbopol 934P and Sterculia gum with Ethyl cellulose at 1:1, 1: .5 and 1:2 ratio. Coating was carried out by using 1:1 ratio of Eudragit L100 and Eudragit S100. All the preparation were evaluated for Pre compressional properties, Post compressional properties and in-vitro Dissolution study in different pH buffer of 0.1N HCL ,pH 7.4 , pH 6.8 in order to mimic GIT condition. Formulation shows good results with good percentage yield.