UJI AKTIVITAS ANTIOKSIDAN DAN TOKSISITAS EKSTRAK AKAR TANAMAN Amaranthus spinosus
Main Authors: | ', M.Almurdani, Jose, Christine, Teruna, Hilwan Yuda |
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Format: | Article info application/pdf eJournal |
Bahasa: | eng |
Terbitan: |
Indonesian Chemia Acta
, 2014
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Online Access: |
http://ejournal.unri.ac.id/index.php/ICA/article/view/1863 http://ejournal.unri.ac.id/index.php/ICA/article/view/1863/1833 |
Daftar Isi:
- The aim of this study was to determine the antioxidant and toxicity activities of n-hexane, ethyl acetate and methanol root extracts of Amaranthus spinosus (family: Amaranthaceae). Antioxidant activities of the crude extracts was assessed by means of DPPH free radical scavenging method used ascorbic acid as standard with IC50 value was 43.22 μg/mL. A. spinosus showed ethyl acetate extract demonstrated the good antioxidant activity with IC50 value of 72,08 μg/mL. The n-hexana and methanol extract were not active antioxidant. The Brine shrimp lethality bioassay method was used to determine the cytotoxicity activities. The LC50 values of n-hexane, ethyl acetate and methanol extracts were 10.14, 40.23, and 120.18 μg/mL, respectively.Keywords: Amaranthus spinosus, antioxidant, DPPH, toxicity