Sintesis Beberapa Senyawa Analog Calkon menggunakan Katalis SOCl2 dan Uji Aktivitas sebagai Antimikroba
| Main Authors: | ', Yuharmen, Eryanti, Yum, Zamri, Adel, Rahmad, Alvi |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Jurnal Teknobiologi
, 2013
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| Online Access: |
http://ejournal.unri.ac.id/index.php/JTB/article/view/1404 http://ejournal.unri.ac.id/index.php/JTB/article/view/1404/1391 |
Daftar Isi:
- Some chalcone analogous have been synthesized from 3’-hydroxyacetophenoneand benzaldehyde derivates by Claisen-Schmidt condensation using thyonyl chlo-ride (SOCl2) catalyst. It produced three compounds i.e. 1-(3-hydroxy-phenyl)-3-(4-hydroxy-phenyl)-prophenone; 1-(3-hydroxy-phenyl)-3-(4-chloro-phenyl) prophe-none and 1-(3- hydroxy-phenyl)-3-(4-nitro- phenyl)-prophenone. The structure ofthe compounds were then characterized using UV, IR and NMR. All of the synthe-sized compounds show antimicrobial activities toward Psedomonas aeruginosa,Bacillus subtilis and Candida albicans.