PROFIL DISOLUSI DAN PENETAPAN KADAR TABLET MELOKSIKAM INOVATOR DAN GENERIK BERMEREK DENGAN KCKT (KROMATOGRAFI CAIR KINERJA TINGGI)
| Main Authors: | Mutiatikum, D.; Pusat Penelitian dan Pengembangan Biomedis dan Farmasi, Jakarta, Raini, Mariana; Pusat Penelitian dan Pengembangan Biomedis dan Farmasi, Jakarta |
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| Other Authors: | BADAN LITBANGKES KEMENKES |
| Format: | application/pdf eJournal |
| Bahasa: | ind |
| Terbitan: |
Badan Penelitian dan Pengembangan Kesehatan
, 2012
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| Subjects: | |
| Online Access: |
http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/101 |
Daftar Isi:
- Abstract. The determination of meloxicam and the dissolution test has been done. Drug dissolution test is an approach to evaluate drug release characteristics of product (Tablets/capsules) in vitro. The tests are conducted for various durations from 5,10,15,20,25,30,40,50 and 60 minutes with appropriate sampling. The method of dissolution test and assay of meloxicam accords with British Pharmacopoeia 2007. A control experiment wih HPLC was performed simoultaneously. The dissolution test of meloxicam at 30 minutes in tablet A is 97.79% and tablet B is 87.78% meet the requirement of the British Pharmacopoeia 2007. The content of meloxicam are in tablet A is 100.26%, tablet B is 104.07%. Both of its meet the requirement of British Pharmacopoeia 2007. The content of meloxicam are in tablet A is 100.26%, tablet B is 104.07%. Both of its meet the requirement of British Pharmacopoeia 2007.Key Words : Meloksikam, KCKT