Perbandingan Penambahan Klonidin Intratekal 15 μg dan 30 μg pada 12,5 mg Bupivakain 0,5% terhadap Kejadian Menggigil Pascaanestesi Spinal pada Seksio Sesarea
| Main Authors: | Yusup Mansur, Iman Muhammad, Pradian, Erwin, Bisri, Tatang |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Faculty of Medicine, Universitas Padjadjaran
, 2015
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| Subjects: | |
| Online Access: |
http://journal.fk.unpad.ac.id/index.php/jap/article/view/376 http://journal.fk.unpad.ac.id/index.php/jap/article/view/376/pdf_38 |
Daftar Isi:
- Menggigil pascaanestesi spinal merupakan efek samping yang sering terjadi. Penelitian ini bertujuan untuk membandingkan penambahan klonidin intratekal antara 15 μg dan 30 μg pada 12,5 mg bupivakain. Penelitian adalah eksperimental dengan uji klinis rancangan acak lengkap terkontrol buta tunggal pada 80 wanita yang menjalani seksio sesarea dengan anestesi spinal, status fisik American Society of Anesthesiologist (ASA) II, berusia 18–42 tahun, dibagi secara random menjadi dua kelompok, kelompok I menggunakan 12,5 mg bupivakain 0,5 % dan klonidin 15 μg, sedangkan kelompok II mendapat penambahan klonidin 30 μg. Penelitian dilakukan di Rumah Sakit Dr. Hasan Sadikin Bandung pada periode Oktober–Desember 2011. Perbandingan proporsi kejadian kedua kelompok dianalisis secara statistik menggunakan uji chi-kuadrat, sedangkan derajat menggigil dengan Uji Mann-Whitney. Hasil penelitian menunjukkan bahwa kejadian menggigil pascaanestesi pada kelompok II sebanyak 2 pasien, sedangkan pada kelompok I adalah 10 pasien. Simpulan, penambahan klonidin intaratekal 30 μg pada bupivacain 0,5% untuk mencegah menggigil pascaanestesi spinal lebih baik dibandingkan dengan klonidin intratekal 15 μg. Kata kunci: Klonidin intratekal, menggigil pascaanestesi, mencegah menggigil, suhu intiComparison of 15 μg and 30 μg Intrathecal Clonidine in 12.5 mg 0.5% Bupivacain for Post Spinal Anesthesia Shivering in Caesarean SectionAbstractShivering is a frequently experienced side effect of post-subarachnoid block. This study aimed to determine the which of 15 μg dose and 30 μg dose of intrathecal Clonidine is better prevents Post anaesthesia shivering. The research was conducting by clinical trials of a single blind randomized controlled design. Eighty pregnant female patients with ASA physical status II, aged 18–42 years, who underwent a caesarean section were randomly divided into two groups, spinal anesthesia performed by using 12.5 0.5% mg bupivacain and 15 μg clonidine in Group I and the same dose of bupicavain but with 30 μg clonidine in group II. The incidence proportion of both groups were statistically compared using chi square test, while the degree of shivering was analyzed using Mann-Whitney test. The results showed that the characteristics of patient data and the core temperature did not statistically different between the two groups. The incidence and degree of shivering were different between the two groups, with were 2 patients experienced shivering incidence in group II and 10 patients experienced the incidence in group I. It is concluded that the addition of intrathecal 30 μg clonidine to 0.5% bupivacain prevents post-subarachnoid spinal block shivering better than in trathecal clonidine 15 μg. Key words: Core temperature, intrathecal clonidine post anaesthesia shivering, prevent shivering