The effect of 0.03% flurbiprofen and 0.1% indomethacin eye drops and oral indomethacin on the pupil diameter in the extracapsular cataract surgery
| Main Author: | Mu'tasimbillah Ghozi, Mu'tasimbillah Ghozi |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | ind |
| Terbitan: |
Journal of the Medical Sciences (Berkala ilmu Kedokteran)
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| Online Access: |
https://journal.ugm.ac.id/bik/article/view/4214 https://journal.ugm.ac.id/bik/article/view/4214/3468 |
Daftar Isi:
- Background: Intraocular surgery releases prostaglandin. Prostaglandin caused miosis and inflammatory reaction. Flurbiprofen and Indomethacin are antiprostaglandin agents.Objectives: This study was aimed to compare the effects of flurbiprofen and indomethacin eye drop and flurbiprofen tablet orally in preventing surgically induced miosis to dilated pupils during extracapsular cataract surgery.Methods: Measurement of the diameter of dilated pupil before and during extracapsular cataract surgery. Analysis variance and Tukey Studentized Rest Test were used to analyse the result.Results: No statitical significant difference was found in pupil diameter among the three groups except the stage of capsulotomy and inspiration-aspiration among those who received flurbiprofen and indomethacin eye drops.Conclusion: Flurbiprofen 0.03% eye drop was significantly stronger than Indomethacine eye drop 0.1% in preventing surgically induced miosis at extracapsular cataract surgery especially in both stage of capsulotomy and inspiration-aspiration and type manipulation.Keywords: cataract surgery - anterior capsulotomy - lens extraction - insiparition-aspiration - miosis -antiprostaglandin