Incision wound healing test ethanolic extract gel from Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves in white male rats
| Main Authors: | Sanik, Fathnur; Pharmacy Study Program, Faculty of Medicine and Public Health Sciences, Jambi University, Rahman, Havizur; Jambi University, Rahman, Ave Olivia; Jambi University, Samudra, Agung Giri; Bengkulu University, Floris, Cassa de; Jambi University, Muhaimin, Muhaimin; Padjadjaran University |
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| Other Authors: | The author would like to thank the Faculty of Medicine and Health Sciences, Jambi University for the applied research grant that comes from the Faculty PNBP fund with contract number 371/UN21.11/PT01.05/SPK/2021. |
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Universitas Ahmad Dahlan
, 2022
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| Subjects: | |
| Online Access: |
http://journal.uad.ac.id/index.php/PHARMACIANA/article/view/22825 http://journal.uad.ac.id/index.php/PHARMACIANA/article/view/22825/pdf_233 |
Daftar Isi:
- Ekor naga (Rhaphidophora pinnata (L.f) Schott) leaves have been researched and tested. So, it was known that the chemical content of secondary metabolites effect wound healing. This study aimed to determine the gel effect of ekor naga leaves extracts as a wound healing medicine. The research method evaluated organoleptic, pH, spreadability, and adhesion of gel preparations which were measured every week for four weeks. The testing of gel effect on the wound healing medicine was being performed. In 5 treatment groups namely positive control: Bioplasenton, Formula 0: negative control, Formula 1: 10% extract concentration, Formula 2: 15% extract concentration, and Formula 3: 20% extract concentration. The result obtained were analyzed by one-way ANOVA and continued by the Duncan test with a level of 95% confidence. The research results showed that formula 3 has the best wound healing effect, followed by formulas 2 and 1. The statistical results have a significant difference (p<0,05), but the results of stability observations of the formula two preparation have a stable. Evaluation value for four weeks of observation with a care effect of 95.3%. So, formula 2 is the best formula for stability and testing wound healing effectiveness.