Lihat Juga

• BIOTRANSFORMATION OF CINCHONA ALKALOID COMPOUNDS BY MOLD Xylaria sp.TO CINCHONA N-OXIDE ALKALOIDS [Studies on Endophytic Microbes of Cinchona spp. plants (5)]
  oleh: Simanjuntak, Partomuan; Biotechnology Center Science Institute of Indonesia Jalan Raya Bogor Km 46 Cibinong 16911, et al.
  Terbitan: (2005)
• Produksi alkaloid kuinina oleh beberapa Mikroba endofit dengan penambahan zat induser (Studi Mikroba Endofit Tanaman Cinchona sp. (2)): Production of quinine alkaloid by some endophytic microbes with addition of inducer
  oleh: Perpustakaan UGM, i-lib
  Terbitan: (2002)
• Cinchona alkaloids are in extensive uses, not only for drugs but also for soft drink industries. They are harvested from the bark of trees Cinchona spp. after certain ages and therefore are available over a limited time. Cell culture is an alternative way to continuously produce such secondary metabolites in a much shorter time. Various substances were added in the normal growth media to promote quinoline alkaloids production by cell cultures of Cinchona ledgeriana. At the sixth week of culture, quinine and cinchonine contents were suppressed by paclobutrazol (PBZ), abscisic acid (ABA), or even by precursor tryptophan, while cinchonidine content was enhanced by 0.2 mg/l tryptophan to 43 fold of that produced by untreated cells (2.8% dry weight). At the seventh week of culture, the production of quinine and quinidine started to grow whereas the production of cinchonine and cinchonidine tended to decrease. An addition of 5 mg/l PBZ to culture media yielded the highest level of total quinine/quinidine after seven weeks, e.g. quinine 11 times more abundant and quinidine 23 fold higher compared to the untreated cells. Particularly the level of quinine which is the most demanded for medical and industrial purposes still need to be improved to approach to or even higher than that of extracted from the conventional source
  oleh: RATNADEWI, DIAH; Department of Biology, Bogor Agricultural University, et al.
  Terbitan: (2011)
• Pachybasin, a Major Metabolite from Culture Broth of Endophytic Coelomyceteous AFKR-18 Fungus isolated from a Yellow Moonsheed Plant, Arcangelisia flava (L.) Merr
  oleh: WULANSARI, DEWI; Phytochemistry Laboratory, Research Center for Biology, Indonesian Institute of Sciences Jalan Raya Bogor Km. 46, Cibinong 16911, Indonesia, et al.
  Terbitan: (2014)
• EFFECT OF METHANOL INDUCTION AND INCUBATION TIME ON EXPRESSION OF HUMAN ERYTHROPOIETIN IN METHYLOTROPIC YEAST Pichia pastoris
  oleh: Adi Santoso; Research Center for Biotechnology, Indonesian Institute of Science, Cibinong, Bogor 16911, Indonesia, et al.
  Terbitan: (2012)