PHYSICAL PROPERTIES OF WOUND HEALING GEL OF ETHANOLIC EXTRACT OF BINAHONG (Anredera cordifolia (Ten) Steenis) DURING STORAGE
Main Authors: | Yuliani, Sri Hartati; Faculty of Pharmacy, Universitas Gadjah Mada, Skip Utara, Yogyakarta 55281 Indonesia Faculty of Pharmacy, Universitas Sanata Dharma, Paingan, Maguwoharjo, Depok, Yogyakarta 55284 Indonesia, Fudholi, Achmad; Faculty of Pharmacy, Universitas Gadjah Mada, Skip Utara, Yogyakarta 55281 Indonesia, Pramono, Suwijiyo; Faculty of Pharmacy, Universitas Gadjah Mada, Skip Utara, Yogyakarta 55281 Indonesia, ., Marchaban; Faculty of Pharmacy, Universitas Gadjah Mada, Skip Utara, Yogyakarta 55281 Indonesia |
---|---|
Format: | Article info eJournal |
Bahasa: | eng |
Terbitan: |
Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia
, 2012
|
Online Access: |
https://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/684 https://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/684/550 |
Daftar Isi:
- Binahong (Anredera cordifolia (Ten) Steenis) has been used as wound healing in traditional Indonesian medicine. The developing of the dosage forms using the formulation technology approach has been done. The aim of this study was to examine the physical properties of the wound healing gel of ethanolic extract of binahong during storage. The factorial design method 3 factors and 2 levels was employed to achieve this study. The three factors used in this study were Carbopol, CMC-Na and Caalginate with low and high level for each factor. The physical properties of the wound healing gel of ethanolic extract of binahong was evaluated on day 1, 30, 60 and 90 for viscosity and bioadhesion study. The result showed that CMC-Na and Caalginate increased the alteration of physical properties of wound healing gel of ethanolic extract of binahong during storage. The carbopol maintained the physical properties of the gel during storage.Key words: bioadhesion, binahong, viscosity, wound healing gel.