APPLICATION OF FOURIER TRANSFORM INFRARED SPECTROSCOPY FOR QUALITY CONTROL OF PHARMACEUTICAL PRODUCTS: A REVIEW
| Main Author: | Rahman, Abdul; Laboratory of Analytical Chemistry, Faculty of Pharmacy, Universitas Gadjah Mada, 55281, Yogyakarta, Indonesia. +62274-543120 |
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| Format: | Article info eJournal |
| Bahasa: | eng |
| Terbitan: |
Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia
, 2012
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| Online Access: |
https://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/656 https://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/656/522 |
Daftar Isi:
- Analysis of pharmaceutical products covers all aspects of quality control of active pharmaceutical ingredients (API) and finished products. Today, Fourier transform infrared (FTIR)spectroscopy, especially in combination with chemometrics software, has emerged as one of the romising analytical techniques to be used in pharmaceutical industry, for quality control of desired pharmaceutical products. Compared with other instrumental techniques, FTIR spectroscopy offers some advantages, namely it is rapid, simple in sample preparation, and not destructive. In this review, the application of FTIR spectroscopy for qualitative and quantitative determinations of API and monitoring drug release are described.Key words: FTIR spectroscopy, quality control, pharmaceutical products.