EVALUATION OF ANTIMICROBIAL POTENTIALS OF Cardiospermum halicacabum Linn
| Main Author: | Veerappan, Loganathan; School of Pharmacy, Taylor’s University, 47500 Subang Jaya, Selangor, Malaysia |
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| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia
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| Online Access: |
http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/65 http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/65/47 |
Daftar Isi:
- Antimicrobial activity of Cardiospermum halicacabumshoot extracts were studied on gram-positive bacteria such asStaphylococcus aureus, Bacillus substilis, and gram-negativebacteria such as E.coli, Proteus vulgaris, and fungus Candidaalbicans. Disc diffusion method was used to study theantimicrobial activity of aqueous, ethanol, chloroform and etherextracts of C. halicacabum. Ampicillin was used as referencestandard at 10 g/disc concentration. Extracts of C. halicacabumexhibited a significant antibacterial activity except the aqueousextract. Ethanolic extract was found to be very effective withmaximum activity index (0.84). The ethanolic extract exhibitedminimum inhibitory concentration (MIC) of 0.25 mg/mL againstStaphylococcus aureus, Bacillus substilis, E. coli and Proteusvulgaris and 0.125 mg/mL against Candida albicans. The MIC ofchloroform and ether extracts ranged between 0.25 and 1.0mg/ml against the test organisms. All the extracts showedantifungal activity against Candida albicans.Key words: antimicrobial activity, Cardiospermum halicacabum shootsystem, solvent extraction