The effect of fumaric acid-sodium bicarbonate on the green tea effervescent granule’s quality made by dry granulation
| Main Authors: | Lestari, Agatha Busi susiati; Faculty of Pharmacy, Sanata Dharma University. Yogyakarta, Indonesia, Trisusilawati, Maria Yuli; Faculty of Pharmacy, Sanata Dharma University. Yogyakarta, Indonesia |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia
, 2010
|
| Online Access: |
http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/470 http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/470/349 |
Daftar Isi:
- Tea plant (Camellia sinensis L.) had been known to contains epigallocathecin gallate (EGCG) that can be used to maintain the healthy. In this research, the green tea was tried to be formulated in effervescent dosage form, with the focus on the effect among fumaric acid, sodium bicarbonate, and the interaction between fumaric acid and sodium bicarbonate on the green tea extract effervescent granule’s physical properties, that made by dry granulation method. Physical properties of effervescent granule that been study were moisture content, flow rate, disintegration time, and pH of the solution. The result showed that sodium bicarbonate was dominant in determining pH, granule flow rate and moisture content of granule, whereas fumaric acid dominant in disintegration time of effervescent granule.Key words: green tea, fumaric acid, effervescent granule, dry granulation