Identification of cubebin and epicubebin isolated from Piper cubeba L.f fruits with two D-NMR spectroscopy
| Main Authors: | ., Wahyono; Faculty of Pharmacy, Gadjah Mada University, Yogyakarta Indonesia, Wahyuono, S.; Faculty of Pharmacy, Gadjah Mada University, Yogyakarta Indonesia, Mursyidi, A.; Faculty of Pharmacy, Gadjah Mada University, Yogyakarta Indonesia, Timmerman, H.; Division of Medicinal Chemistry, Department of Pharmacochemistry, VrijeUniversiteit, The Netherlands, Verpoorte, R.; Department of Pharmacognosy, Gorleaus Laboratory, Leiden University, The Netherlands, Hakim, L.; Faculty of Pharmacy, Gadjah Mada University, Yogyakarta Indonesia |
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| Format: | Article info eJournal |
| Bahasa: | eng |
| Terbitan: |
Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia
, 2005
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| Online Access: |
http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/433 http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/433/312 |
Daftar Isi:
- One of the isolated active compound of the tracheospasmolytic from kemukus fruits (Piper cubeba L.f) is cubebin. The problem occurred when cubebin (C20H20O6) mixed with its epimer because of the difficultly to identify the structure by 1D-NMR spectroscopy. Structure identification then was conducted by 2D-NMR spectroscopy, so the structure of cubebin and epicubebin can be clear identified. Key words : Cubebin, epicubebin, identification, 2D-NMR