Effect of ethanol extract of Erythrina fusca Lour (cangkring) leaves on suppression of cyclooxygenase-2 expression in raji cell line
| Main Authors: | Ikawati, Zullies; Faculty of Pharmacy Universitas Gadjah Mada Yogyakarta, Nugroho, Agung Endro; Faculty of Pharmacy Universitas Gadjah Mada Yogyakarta, Werdhinindah, Winda; Faculty of Pharmacy Universitas Gadjah Mada Yogyakarta |
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| Format: | Article info eJournal |
| Bahasa: | eng |
| Terbitan: |
Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia
, 2006
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| Online Access: |
http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/348 http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/348/229 |
Daftar Isi:
- COX-2. COX-2 is expressed highly in inflammation and cancer cells. The effect of ethanol extract of Erythrina fusca Lour (cangkring) toward suppression of COX-2 expression in Raji cells was studied using immunocytochemistry method. This research showed that ethanol extract of E. fusca Lour leaves on concentration of 250,0; 125,0; dan 62,50 μg/mL was able to suppress the COX-2 expression significantly in comparison to control, with the inhibition of 70,19 ± 2,14 %; 44,69 ± 1,62 %; and 23,25 ± 2,21 %.Key words: COX-2 expression, anti-inflammation, anti cancer, Raji cells, ethanol extract of E. fusca leaves, immunocytochemistry