Daftar Isi: THERAPEUTIC MILD HYPOTHERMIA TOWARDS BLOOD LACTATE LEVELS AND GLASGOW COMA SCORE IN SEVERE TRAUMATIC BRAIN INJURY

Main Authors:	Pardamean, D. T.; Department of Surgery, Neurosurgery Division, Prof. Dr. R. D. Kandou Hospital/School of Medicine, University of Sam Ratulangi, Manado-Indonesia, Prasetyo, E.; Department of Surgery, Neurosurgery Division, Prof. Dr. R. D. Kandou Hospital/School of Medicine, University of Sam Ratulangi, Manado-Indonesia, Oley, M.; Department of Surgery, Neurosurgery Division, Prof. Dr. R. D. Kandou Hospital/School of Medicine, University of Sam Ratulangi, Manado-Indonesia
Other Authors:	Department of Surgery, Neurosurgery Division, Prof. Dr. R. D. Kandou Hospital/School of Medicine, University of Sam Ratulangi, Manado-Indonesia
Format:	Article application/pdf eJournal
Bahasa:	eng
Terbitan:	BALI MEDICAL JOURNAL , 2016
Subjects:	severe brain metabolism reduction improved
Online Access:	http://ojs.unud.ac.id/index.php/bmj/article/view/21705

Daftar Isi:

Background: Raised body temperature is a common occurrence after severe traumatic brain injury (TBI). TBI is accompanied by regional alterations of brain metabolism, reduction in metabolic rates and possible energy crisis. This metabolic disturbance reflected by increase and accumulation of the brain lactate levels. The study aimed to evaluate the effect of therapeutic mild hypotermia (TMH) on lactate levels and GCS (Glasgow Coma Score) of severe TBI. Methods: Fourthy patients with TBI were randomly divided into normothermia (n=20) and mild hypothermia (n=20) group. Body temperature of hypothermia group was maintained at 35°C for 72 hours. Blood lactate level and GCS were determined before and after hypothermia therapy ( on 3th and 7th day). Results: The mean lactate {5.370 vs 4.025 mmol/L, p