Diamond Light Source DiamondMX protein structure BLAST Bacteroides Bacteroides xylanisolvens CMAH GH99 GlycoPOISE Neu5Ac Neu5Gc endomannanase endomannosidase fasta glycobiology glycoside hydrolase glycosylation iqtree maximum likelihood phylogenetics phylogeny protein sialic acid tree BxGH99 GDP-Man GT108 Leishmania Leishmania mexicana Trypanosomatidae aziridine carbasugar carbohydrate reserve central carbon metabolism crystallography diffraction images glycan phosphorylase glycosidase glycosyltransferase horizontal gene transfer iminosugar leishmaniasis mannogen mannoimidazole mannose mannosidase mannosyltransferase parasite pathogenesis phosphorylase