pulmonary artery hypertension atrial septal defect cardiology cardiovascular medicine hypertension 6-minute walk test COVID-19 ETD Hypertension P-wave dispersion alcohol consumption atrial arrhytmia atrial fibrillation bronchial artery embolization chronic heart failure - scoring system - electrocardiogram features - type of heart failure congenital heart disease– associated PAH diastolic dysfunction eating pattern eccentricity index elderly fat function functional capacity gene mutation heart failure hemoptysis mean pulmonary arterial pressure pathogenesis pulmonary arterial hypertension pulmonary hypertension pulmonary vascular remodeling right ventricle systolic risk factor secundum atrial septal defect severity soluble ST2