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Topik: Direct compression
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Direct compression
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Bioavailability
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Buoyancy
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Chlorpheniramine maleate
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Citric acid
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Floating Drug Delivery
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Gossypium herbaceum
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Microcrystalline cellulose
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Physico-chemical properties
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Spherical agglomerates
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Tablet
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The present study was undertaken with an aim to design
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develop and evaluate floating tablet of Rabeprazole
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friability
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gas generating agent sodium bicarbonate and citric acid. The high level of HPMC K15M and citric acid favors preparation of floating tablet Rabeprazole. The tablets were prepared by direct compression techniques and evaluated thickness
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hardness
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superdisintegrant
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weight variation
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which release the drug in a sustained manner over a period of 12 hours. In this resesrch work used hydroxy propyl methyl cellulose(HPMC K15M)
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