UJI KARAKTERISTIK FISIK DAN AKTIVITAS ANTIBAKTERI KRIM EKSTRAK ETANOL BAWANG DAYAK (Eleutherine palmifolia) (Terhadap Staphylococcus aureus)
Daftar Isi:
- Background : Dayak onion have antibacterial compound napthoquinone that can inhibit the growth of Staphyloccocus aureus. Therefore, it can be made as an antibacterial agent of cream preparation. Cream preparations were chosen because they are easy to use, easy to wash with water, and not sticky. Type of cream o/w are chosen because easily spread evenly, practically, leaving an oily layer or film on the skin, the work takes place on local tissue. Purposes : This study is to determine the effect of Dayak Onion ethanol extract concentrations 2%, 4%, and 6% on the physical characteristics of cream preparation and their antibacterial activity against Staphylococcus aureus. Method : Dayak Onion Ethanol Extract formulated into cream in three formulas, FI (2%), FII (4%), and FIII (6%). Physical characteristic tests included organoleptic, type of emulsion, homogeneity, pH, viscosity, and spreadability. The antibacterial activity are tested by well diffusion method. Result : Physical characteristics results showed organoleptic of cream is yellowish color, smell typical Dayak Onion, soft, homogeneous, and emulsion type is o/w. The increase in concentration of extract can reduce pH and spreadability, and increase the viscosity of cream preparation. The antibacterial test results showed FI (7.50±0.05) mm, FII (8.43±0.01) mm, and FIII (9.35±0.05) mm. Increasing concentration of extract significantly affected the increase in bacterial inhibition zone in cream preparations. Conclusions : Cream antibacterial of FIII (concentrastion extract 6%) has the best physical characteristics and antibacterial activity against Staphylococcus aureus.