UJI TOKSISITAS AKUT DARI EKSTRAK KULIT BUAH RAMBUTAN (Nepheliumlappaceum L.) YANG BERPOTENSI SEBAGAI OBAT HERBAL ANTIDIABETES
| Main Authors: | -, Muhtadi, -, Haryoto, Sujono, Tanti Azizah, Suhendi, Andi |
|---|---|
| Format: | Article info application/pdf eJournal |
| Bahasa: | eng |
| Terbitan: |
Universitas Muhammadiyah Semarang
, 2015
|
| Online Access: |
http://jurnal.unimus.ac.id/index.php/psn12012010/article/view/1567 http://jurnal.unimus.ac.id/index.php/psn12012010/article/view/1567/1619 |
Daftar Isi:
- The acutetoxicitytestinghave been conducted inthe male and female ratsSD strain oframbutan (Nepheliumlappaceum L.)fruitpeel extract. The testing had been doneby providingwitha doserankedasfollows: the firstdose; 0mg/kgBW, doseII; 400mg/kgBW, doseIII; 1,400mg/kgBW, IVdoses; 4,900mg/kgBW, and thedosage ofV; 17,150mg/ kgBW for 14days. Thenit had been observedclinical symptomsthat happened, changed in body weightperweekanddefect on vital organs, namely: the liver, kidneys, stomach, intestines, spleen, heartandlungs. Theresults ofthis study was concludedthat thehighest doseof up to17,150mg/kgBW ofthe extract, safety andproved to be not toxic to thefemaleandmaleratsSDstrain.Keywords : The acutetoxicitytesting; rambutanfruitpeel extract; thefemaleandmaleratsSDstrain.