Lokasi: HIGHLY SENSITIVE VOLTAMMETRIC DETERMINATION OF DANTROLENE SODIUM IN PURE FORM, PHARMACEUTICALS, HUMAN BREAST MILK AND URINE AT PENCIL GRAPHITE AND GLASSY CARBON ELECTRODES

Main Author:	Marwa A.Omran
Format:	Article Journal
Terbitan:	, 2016
Subjects:	Voltammetric behavior of dantrolene sodium (Dan) was comparatively investigated in Britton Robinson (BR) buffer as electrolyte at pencil graphite (PGE) and glassy carbon (GCE) electrodes cyclic voltammetry (CV) gave one reversible cathodic anodic peak at -0.302 -0.249 V at PGE and -0.257 -0.178 V at GCE respectively and another irreversible cathodic one at -0.748 at PGE and -0.694 V at GCE. Differential pulse (DPV) and square wave (SWV) voltammetry were investigated for the reversible cathodic peak and gave at PGE linearity range from 0.395-2.955 and 0.395-1.9 μg/mL with correlation coefficient 0.999 for both LOD 0.09 and 0.052μg/mL LOQ 0.273 and 0.158 μg/mL respectively and at GCE linearity range from 0.974- 2.44 and 0.199- 2.96 μg/mL with correlation coefficient 0.999 for both LOD 0.167 and 0.095 μg/mL LOQ 0.507 and 0.289 μg/mL respectively. The proposed procedures were successfully applied to the determination of Dan with good recovery in pharmaceutical dosage form human mother milk and urine directly without any pretreatment at both electrodes. The techniques were validated and revealed good accuracy and reproducible results. Keywords: Dantrolene Sodium Biological fluids pencil graphite electrode glassy carbon electrode Pharmaceuticals Voltammetry
Online Access:	https://zenodo.org/record/166018

Koleksi	Cognizance Journal of Multidisciplinary Studies
Gedung	Cognizance Journal of Multidisciplinary Studies
Institusi	ZAIN Publications
Kota	Stockholm
Provinsi	INTERNASIONAL
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