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Advances in understanding and drug development for ALK2/ACVR1 gain of function mutations in Diffuse Intrinsic Pontine Glioma (DIPG)

Tersimpan di:
Main Authors: Wong, Jong Fu, Brown, Elizabeth, Williams, Eleanor, Adamson, Ros, Farnie, Gillian, Boudhar, Aicha, Brennan, Paul E, Edwards, Aled M, Bullock, Alex N
Format: Proceeding poster
Terbitan: , 2018
Subjects:
CRUK brain tumour conference 2018
DIPG
diffuse intrinsic pontine glioma
M4K Pharma
ALK2
ACVR1
inhibitor development
kinase inhibitors
Online Access: https://zenodo.org/record/1246855
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Internet

https://zenodo.org/record/1246855

Lihat Juga

  • Understanding the pathogenic mechanism of ACVR1 mutations in Diffuse Intrinsic Pontine Glioma
    oleh: Brown, Elizabeth, et al.
    Terbitan: (2018)
  • Sequencing of ACVR1/ALK2 in patient derived DIPG cell lines
    oleh: Brown, Elizabeth, et al.
    Terbitan: (2019)
  • Determining the dual luciferase ALK5 IC50 values of 30 legacy ACVR1/ALK2 inhibitors
    oleh: Jong Fu Wong, et al.
    Terbitan: (2018)
  • Growth kinetics of the HSJD-DIPG-07 cell line in non-adherent culture
    oleh: Brown, Elizabeth, et al.
    Terbitan: (2018)
  • Evaluating the inhibition of ALK2 phosphorylation of SMAD1/5 by M4K lead compounds in DIPG patient-derived cells (SU-DIPG-IV, HSJD-DIPG-007, HSJD-DIPG-018 and SU-DIPG-XXI)
    oleh: Jong Fu Wong, et al.
    Terbitan: (2020)
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